MedKoo Cat#: 56571 | Name: AMXT1501

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AMXT1501 is a polyamine uptake inhibitor, also inhibiting the putrescine transport in epimastigotes (the insect stage of t. cruzi)

Chemical Structure

AMXT1501
AMXT1501
CAS#441022-64-6

Theoretical Analysis

MedKoo Cat#: 56571

Name: AMXT1501

CAS#: 441022-64-6

Chemical Formula: C32H68N6O2

Exact Mass: 568.5404

Molecular Weight: 568.94

Elemental Analysis: C, 67.56; H, 12.05; N, 14.77; O, 5.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AMXT-1501; AMXT 1501; AMXT1501
IUPAC/Chemical Name
(S)-N-(5-Amino-6-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-6-oxohexyl)palmitamide
InChi Key
USNCWPSRPOWEBG-PMERELPUSA-N
InChi Code
InChI=1S/C32H68N6O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-22-31(39)37-28-16-15-21-30(34)32(40)38-29-20-27-36-25-18-17-24-35-26-19-23-33/h30,35-36H,2-29,33-34H2,1H3,(H,37,39)(H,38,40)/t30-/m0/s1
SMILES Code
CCCCCCCCCCCCCCCC(NCCCC[C@H](N)C(NCCCNCCCCNCCCN)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 568.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hirano R, Kujirai T, Negishi L, Kurumizaka H. Biochemical characterization of the placeholder nucleosome for DNA hypomethylation maintenance. Biochem Biophys Rep. 2019 Apr 10;18:100634. doi: 10.1016/j.bbrep.2019.100634. eCollection 2019 Jul. PubMed PMID: 31008378; PubMed Central PMCID: PMC6458450. 2: Rose D, Nichols S. Teleological Essentialism. Cogn Sci. 2019 Apr;43(4):e12725. doi: 10.1111/cogs.12725. PubMed PMID: 31001881. 3: Fang J, Liu Y. Ossified chronic subdural hematoma in children: a case report. World Neurosurg. 2019 Mar 26. pii: S1878-8750(19)30822-8. doi: 10.1016/j.wneu.2019.03.144. [Epub ahead of print] PubMed PMID: 30926556. 4: King C, Llewellyn C, Shahmanesh M, Abraham C, Bailey J, Burns F, Clark L, Copas A, Howarth A, Hughes G, Mercer C, Miners A, Pollard A, Richardson D, Rodger A, Roy A, Gilson R. Sexual risk reduction interventions for patients attending sexual health clinics: a mixed-methods feasibility study. Health Technol Assess. 2019 Mar;23(12):1-122. doi: 10.3310/hta23120. PubMed PMID: 30916641; PubMed Central PMCID: PMC6452239. 5: Richter D, Bayer K, Toesko T, Schuster S. ZeBRα a universal, multi-fragment DNA-assembly-system with minimal hands-on time requirement. Sci Rep. 2019 Feb 27;9(1):2980. doi: 10.1038/s41598-019-39768-0. PubMed PMID: 30814590; PubMed Central PMCID: PMC6393441. 6: Uslucan L, Atalay B, Oral CK, Yıldırım MS, Çankaya AB. The histopathological effects of calcium triglyceride bone cement and chitosan on the healing of experimental bone defects. Turk J Med Sci. 2018 Dec 12;48(6):1268-1277. doi: 10.3906/sag-1706-33. PubMed PMID: 30542298. 7: Shukla M, Tong P, White SA, Singh PP, Reid AM, Catania S, Pidoux AL, Allshire RC. Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle. Curr Biol. 2018 Dec 17;28(24):3924-3936.e4. doi: 10.1016/j.cub.2018.10.049. Epub 2018 Nov 29. PubMed PMID: 30503616; PubMed Central PMCID: PMC6303189. 8: Bartsch MV, Donohue SE, Strumpf H, Schoenfeld MA, Hopf JM. Enhanced spatial focusing increases feature-based selection in unattended locations. Sci Rep. 2018 Oct 31;8(1):16132. doi: 10.1038/s41598-018-34424-5. PubMed PMID: 30382137; PubMed Central PMCID: PMC6208401. 9: Gelman SA, Cimpian A, Roberts SO. How deep do we dig? Formal explanations as placeholders for inherent explanations. Cogn Psychol. 2018 Nov;106:43-59. doi: 10.1016/j.cogpsych.2018.08.002. Epub 2018 Sep 4. PubMed PMID: 30189296. 10: Khan HJ, DiCarlo D, Prodanović M. Replicating carbonaceous vug in synthetic porous media. MethodsX. 2018 Jul 29;5:808-811. doi: 10.1016/j.mex.2018.07.018. eCollection 2018. PubMed PMID: 30105214; PubMed Central PMCID: PMC6086142. 11: Sikela JM, van Roy F. Changing the name of the NBPF/DUF1220 domain to the Olduvai domain. Version 2. F1000Res. 2017 Dec 28 [revised 2018 Jan 1];6:2185. doi: 10.12688/f1000research.13586.2. eCollection 2017. PubMed PMID: 29399325; PubMed Central PMCID: PMC5773923.2. 12: Poppe J, Reichelt J, Blankenfeldt W. Pseudomonas aeruginosa pyoverdine maturation enzyme PvdP has a noncanonical domain architecture and affords insight into a new subclass of tyrosinases. J Biol Chem. 2018 Sep 21;293(38):14926-14936. doi: 10.1074/jbc.RA118.002560. Epub 2018 Jul 20. PubMed PMID: 30030378; PubMed Central PMCID: PMC6153295. 13: Lawrence RK, Edwards M, Goodhew SC. Changes in the spatial spread of attention with ageing. Acta Psychol (Amst). 2018 Jul;188:188-199. doi: 10.1016/j.actpsy.2018.06.009. Epub 2018 Jun 29. PubMed PMID: 29982037. 14: Hill FCE, Grenness A, Withers S, Iseli C, Briggs R. Cochlear Patency After Translabyrinthine Vestibular Schwannoma Surgery. Otol Neurotol. 2018 Aug;39(7):e575-e578. doi: 10.1097/MAO.0000000000001858. PubMed PMID: 29912821. 15: Puntiroli M, Kerzel D, Born S. Placeholder objects shape spatial attention effects before eye movements. J Vis. 2018 Jun 1;18(6):1. doi: 10.1167/18.6.1. PubMed PMID: 29860399. 16: Garg AD, Krysko DV, Vandenabeele P, Agostinis P. Author Correction: Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin. Cancer Immunol Immunother. 2018 Jul;67(7):1179-1180. doi: 10.1007/s00262-018-2162-8. PubMed PMID: 29737376. 17: Quiles C, Constantino JA, Gañán Y, Macías D, Quiles M. Stereophotogrammetric surface anatomy of the anterior cruciate ligament's tibial footprint: Precise osseous structure and distances to arthroscopically-relevant landmarks. Knee. 2018 Aug;25(4):531-544. doi: 10.1016/j.knee.2018.03.016. Epub 2018 Apr 26. PubMed PMID: 29705076. 18: Bobkov GOM, Gilbert N, Heun P. Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation. J Cell Biol. 2018 Jun 4;217(6):1957-1972. doi: 10.1083/jcb.201611087. Epub 2018 Apr 6. PubMed PMID: 29626011; PubMed Central PMCID: PMC5987708. 19: Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Cell. 2018 Feb 22;172(5):993-1006.e13. doi: 10.1016/j.cell.2018.01.022. Epub 2018 Feb 15. PubMed PMID: 29456083. 20: Reigada C, Phanstiel O 4th, Miranda MR, Pereira CA. Targeting polyamine transport in Trypanosoma cruzi. Eur J Med Chem. 2018 Mar 10;147:1-6. doi: 10.1016/j.ejmech.2018.01.083. Epub 2018 Jan 31. PubMed PMID: 29421567.