MedKoo Cat#: 565668 | Name: THRX160209

Description:

WARNING: This product is for research use only, not for human or veterinary use.

THRX160209 is a novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the m2 muscarinic receptor

Chemical Structure

THRX160209
THRX160209
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565668

Name: THRX160209

CAS#: N/A

Chemical Formula: C42H60N4O3

Exact Mass: 668.4665

Molecular Weight: 668.97

Elemental Analysis: C, 75.41; H, 9.04; N, 8.38; O, 7.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
THRX160209; THRX 160209; THRX-160209
IUPAC/Chemical Name
(S)-2-(1-(7-((1-(2,6-Dimethoxybenzyl)piperidin-4-yl)(propyl)amino)heptyl)pyrrolidin-3-yl)-2,2-diphenylacetamide
InChi Key
AXSAVLPYCZEECW-PSXMRANNSA-N
InChi Code
InChI=1S/C42H60N4O3/c1-4-26-46(37-24-30-45(31-25-37)33-38-39(48-2)21-16-22-40(38)49-3)28-15-7-5-6-14-27-44-29-23-36(32-44)42(41(43)47,34-17-10-8-11-18-34)35-19-12-9-13-20-35/h8-13,16-22,36-37H,4-7,14-15,23-33H2,1-3H3,(H2,43,47)/t36-/m1/s1
SMILES Code
O=C(N)C(C1=CC=CC=C1)([C@H]2CN(CCCCCCCN(C3CCN(CC4=C(OC)C=CC=C4OC)CC3)CCC)CC2)C5=CC=CC=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
1: Steinfeld T, Mammen M, Smith JA, Wilson RD, Jasper JR. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor. Mol Pharmacol. 2007 Aug;72(2):291-302. Epub 2007 May 3. PubMed PMID: 17478612.

Preparing Stock Solutions

The following data is based on the product molecular weight 668.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL