MedKoo Cat#: 565623 | Name: MPT0B451

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MPT0B451 is a novel dual hdac6 and tubulin inhibitor, displaying anti-tumor ability in human cancer cells

Chemical Structure

MPT0B451
MPT0B451
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565623

Name: MPT0B451

CAS#: N/A

Chemical Formula: C28H26N2O9S

Exact Mass: 566.1359

Molecular Weight: 566.58

Elemental Analysis: C, 59.36; H, 4.63; N, 4.94; O, 25.41; S, 5.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MPT0B451; MPT 0 B 451; MPT-0-B-451
IUPAC/Chemical Name
(E)-N-Hydroxy-3-(3-((6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)sulfonyl)phenyl)acrylamide
InChi Key
VYTJGUNWINJKES-DHZHZOJOSA-N
InChi Code
InChI=1S/C28H26N2O9S/c1-36-19-9-10-21-22(27(32)18-13-24(37-2)28(39-4)25(14-18)38-3)16-30(23(21)15-19)40(34,35)20-7-5-6-17(12-20)8-11-26(31)29-33/h5-16,33H,1-4H3,(H,29,31)/b11-8+
SMILES Code
O=C(NO)/C=C/C1=CC=CC(S(=O)(N2C=C(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C4=C2C=C(OC)C=C4)=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 566.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wu YW, Hsu KC, Lee HY, Huang TC, Lin TE, Chen YL, Sung TY, Liou JP, Hwang-Verslues WW, Pan SL, HuangFu WC. A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo. Front Pharmacol. 2018 Mar 13;9:205. doi: 10.3389/fphar.2018.00205. eCollection 2018. PubMed PMID: 29593536; PubMed Central PMCID: PMC5859083.