BKM1972 is a novel inhibitor of the expression of anti-apoptotic protein survivin and membrane-bound efflux pump atp binding cassette b 1 (abcb1, p-glycoprotein), presumably via signal transducer and activator of transcription 3 (stat3), inhibiting human prostate cancer growth and overcoming docetaxel resistance in intraosseous models
MedKoo Cat#: 565608
Name: BKM1972
CAS#: N/A
Chemical Formula: C38H44Cl2N2O8P2
Exact Mass: 788.1950
Molecular Weight: 789.62
Elemental Analysis: C, 57.80; H, 5.62; Cl, 8.98; N, 3.55; O, 16.21; P, 7.85
The following data is based on the product molecular weight 789.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
