PW69 significantly delayed ricin-induced cell death. It suppressed activity of the executioner caspases 3/7 in ricin toxin- and Shiga toxin 2-treated cells. It has potential to down-regulate inflammatory signaling pathways associated with exposure to the RIP family of toxins.
MedKoo Cat#: 565563
Name: PW69
CAS#: N/A
Chemical Formula: C25H24N2O2S
Exact Mass: 416.1558
Molecular Weight: 416.54
Elemental Analysis: C, 72.09; H, 5.81; N, 6.73; O, 7.68; S, 7.70
The following data is based on the product molecular weight 416.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
