IUPAC/Chemical Name
Ethyl 3',4',5'-trimethoxythionocinnamate
InChi Key
JUABUGKQZWXRLB-VOTSOKGWSA-N
InChi Code
InChI=1S/C14H18O4S/c1-5-18-13(19)7-6-10-8-11(15-2)14(17-4)12(9-10)16-3/h6-9H,5H2,1-4H3/b7-6+
SMILES Code
S=C(OCC)/C=C/C1=CC(OC)=C(OC)C(OC)=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
282.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kumar S, Singh BK, Prasad AK, Parmar VS, Biswal S, Ghosh B. Ethyl 3',4',5'-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors. Eur J Pharmacol. 2013 Jan 30;700(1-3):32-41. doi: 10.1016/j.ejphar.2012.12.004. Epub 2012 Dec 20. PubMed PMID: 23261968.
2: Kumar S, Mabalirajan U, Rehman R, Singh BK, Parmar VS, Prasad AK, Biswal S, Ghosh B. A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model. Int Immunopharmacol. 2013 Jan;15(1):150-9. doi: 10.1016/j.intimp.2012.10.024. Epub 2012 Nov 5. PubMed PMID: 23137769.
3: Kumar S, Singh BK, Arya P, Malhotra S, Thimmulappa R, Prasad AK, Van der Eycken E, Olsen CE, DePass AL, Biswal S, Parmar VS, Ghosh B. Novel natural product-based cinnamates and their thio and thiono analogs as potent inhibitors of cell adhesion molecules on human endothelial cells. Eur J Med Chem. 2011 Nov;46(11):5498-511. doi: 10.1016/j.ejmech.2011.09.008. Epub 2011 Sep 16. PubMed PMID: 21955679.
