MedKoo Cat#: 565524 | Name: UCPH-102F

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UCPH-102F is a fluorescent excitatory amino acid transporter subtype 1 (eaat1) selective inhibitor

Chemical Structure

UCPH-102F
UCPH-102F
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565524

Name: UCPH-102F

CAS#: N/A

Chemical Formula: C24H25N3O4

Exact Mass: 419.1845

Molecular Weight: 419.48

Elemental Analysis: C, 68.72; H, 6.01; N, 10.02; O, 15.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
UCPH-102F; UCPH 102F; UCPH102F
IUPAC/Chemical Name
2'-Amino-7-(diethylamino)-4'-methyl-2,5'-dioxo-5',6',7',8'-tetrahydro-2H,4'H-[4,7'-bichromene]-3'-carbonitrile
InChi Key
QJLRINQORPQZLU-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25N3O4/c1-4-27(5-2)15-6-7-16-17(11-22(29)30-20(16)10-15)14-8-19(28)23-13(3)18(12-25)24(26)31-21(23)9-14/h6-7,10-11,13-14H,4-5,8-9,26H2,1-3H3
SMILES Code
N#CC1=C(N)OC2=C(C(CC(C(C3=C(O4)C=C(N(CC)CC)C=C3)=CC4=O)C2)=O)C1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 419.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Erichsen MN, Hansen J, Ruiz JA, Demmer CS, Abrahamsen B, Bastlund JF, Bundgaard C, Jensen AA, Bunch L. Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs. Neurochem Res. 2014 Oct;39(10):1964-79. doi: 10.1007/s11064-014-1264-8. Epub 2014 Feb 28. PubMed PMID: 24682739. 2: Huynh TH, Abrahamsen B, Madsen KK, Gonzalez-Franquesa A, Jensen AA, Bunch L. Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102. Bioorg Med Chem. 2012 Dec 1;20(23):6831-9. doi: 10.1016/j.bmc.2012.09.049. Epub 2012 Oct 2. PubMed PMID: 23072958.