MedKoo Cat#: 565468 | Name: ONO-AE3-237

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ONO-AE3-237 is a potent, selective, and orally active prostaglandin d2 receptor antagonist

Chemical Structure

ONO-AE3-237
ONO-AE3-237
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565468

Name: ONO-AE3-237

CAS#: N/A

Chemical Formula: Chemical Formula: C29H28N2O5 Exact Mass: 484.1998 Molecular Weight: 484.5520 Elemental Analysis: C, 71.88; H, 5.82; N, 5.78; O, 16.51

Exact Mass: 484.1998

Molecular Weight: 484.55

Elemental Analysis: C, 71.88; H, 5.82; N, 5.78; O, 16.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ONO-AE3-237; ONO AE3 237; ONOAE3237
IUPAC/Chemical Name
[1-(4-{[(2S)-4,6-Dimethyl-3,4-dihydro-2H-1,4-benzoxazin-2-yl]methoxy}benzoyl)-2-methyl-1H-indol-4-yl]acetic acid
InChi Key
PDLHJVXUGHZZQP-QHCPKHFHSA-N
InChi Code
InChI=1S/C29H28N2O5/c1-18-7-12-27-26(13-18)30(3)16-23(36-27)17-35-22-10-8-20(9-11-22)29(34)31-19(2)14-24-21(15-28(32)33)5-4-6-25(24)31/h4-14,23H,15-17H2,1-3H3,(H,32,33)/t23-/m0/s1
SMILES Code
O=C(O)CC1=CC=CC2=C1C=C(C)N2C(C3=CC=C(OC[C@H]4OC5=CC=C(C)C=C5N(C)C4)C=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 484.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bassiouni W, Daabees T, Norel X, Senbel AM. Hypoactivity of rat detrusor muscle in a model of cystitis: exacerbation by non-selective COX inhibitors and amelioration by a selective DP(1) receptor antagonist. Naunyn Schmiedebergs Arch Pharmacol. 2019 Apr;392(4):437-450. doi: 10.1007/s00210-018-01599-7. Epub 2018 Dec 14. PubMed PMID: 30552456.