MedKoo Cat#: 573730 | Name: allo-DL-Threonine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

allo-DL-Threonine is a racemic mixture of the D and L isomers of the polar essential amino acid threonine. Threonine is the second or third limiting amino acid in swine or poultry diets. This nutrient plays a critical role in the maintenance of intestinal mucosal integrity and barrier function, which can be indicated by intestinal morphology, mucus production (number of goblet cells), transepithelial permeability, brush border enzyme activity, and growth performance.

Chemical Structure

allo-DL-Threonine
CAS#144-98-9

Theoretical Analysis

MedKoo Cat#: 573730

Name: allo-DL-Threonine

CAS#: 144-98-9

Chemical Formula: C4H9NO3

Exact Mass: 119.0582

Molecular Weight: 119.12

Elemental Analysis: C, 40.33; H, 7.62; N, 11.76; O, 40.29

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
1g USD 850.00 2 Weeks
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Related CAS #
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Synonym
allo-DL-Threonine
IUPAC/Chemical Name
2-amino-3-hydroxybutanoic acid
InChi Key
AYFVYJQAPQTCCC-UHFFFAOYSA-N
InChi Code
1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)
SMILES Code
O=C([C@@H]([C@@H](O)C)N)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 119.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Malinovsky AV. Why Threonine Is an Essential Amino Acid in Mammals and Birds: Studies at the Enzyme Level. Biochemistry (Mosc). 2018 Jul;83(7):795-799. doi: 10.1134/S0006297918070039. Review. PubMed PMID: 30200864. 2: Malinovsky AV. Reason for Indispensability of Threonine in Humans and Other Mammals in Comparative Aspect. Biochemistry (Mosc). 2017 Sep;82(9):1055-1060. doi: 10.1134/S0006297917090097. Review. PubMed PMID: 28988535. 3: Rosenthal RG, Vögeli B, Wagner T, Shima S, Erb TJ. A conserved threonine prevents self-intoxication of enoyl-thioester reductases. Nat Chem Biol. 2017 Jul;13(7):745-749. doi: 10.1038/nchembio.2375. Epub 2017 May 15. PubMed PMID: 28504678; PubMed Central PMCID: PMC5892710.