MedKoo Cat#: 565444 | Name: Thiethylperazine Maleate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thiethylperazine Maleate is a dopamine antagonist which blocks postsynaptic dopamine 2 (D2) receptors.

Chemical Structure

Thiethylperazine Maleate
Thiethylperazine Maleate
CAS#1179-69-7

Theoretical Analysis

MedKoo Cat#: 565444

Name: Thiethylperazine Maleate

CAS#: 1179-69-7

Chemical Formula: C30H37N3O8S2

Exact Mass:

Molecular Weight: 631.76

Elemental Analysis: C, 57.04; H, 5.90; N, 6.65; O, 20.26; S, 10.15

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 850.00 2 Weeks
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Related CAS #
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Synonym
Toresten; Tresten; Torecan maleate; Torecan bimaleate; Torecan dimaleate; Thiethylperazine Maleate
IUPAC/Chemical Name
2-Ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleate
InChi Key
RVBRTNPNFYFDMZ-SPIKMXEPSA-N
InChi Code
InChI=1S/C22H29N3S2.2C4H4O4/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24;2*5-3(6)1-2-4(7)8/h4-5,7-10,17H,3,6,11-16H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
SMILES Code
CN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(SCC)C=C24)CC1.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 631.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mendenhall A, Hoyt DB. Incompatibility of ketorolac tromethamine with haloperidol lactate and thiethylperazine maleate. Am J Hosp Pharm. 1994 Dec 1;51(23):2964. PubMed PMID: 7879809. 2: Corea RT. Dislocation of temporomandibular joints resulting from thiethylperazine maleate therapy. Ceylon Med J. 1984 Jun;29(2):117-8. PubMed PMID: 6529785. 3: LOVELACE FR, POE MF, DORNETTE WH. A CLINICAL EVALUATION OF THE ANTIEMETIC PROPERTIES OF THIETHYLPERAZINE MALEATE. Anesth Analg. 1963 Nov-Dec;42:653-7. PubMed PMID: 14071390. 4: GORDON ES, GOLDBERG M, CHOSY GJ. EVALUATION OF THIETHYLPERAZINE MALEATE. JAMA. 1963 Oct 5;186:61-2. PubMed PMID: 14046660. 5: DOBKIN AB, ROBIDOUX HJ Jr, ISRAEL JS. Circulatory response to tilt with hydroxyzine, thiethylperazine maleate, SA 97. and perphenazine. Anesth Analg. 1963 Mar-Apr;42:225-31. PubMed PMID: 14028223.