PUN30119, also known as Imidazole Ketone Erastin, is an inducer of ferroptosis.1 It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 555565
Name: PUN30119
CAS#: 1801530-11-9
Chemical Formula: C35H35ClN6O5
Exact Mass: 654.2357
Molecular Weight: 655.15
Elemental Analysis: C, 64.17; H, 5.39; Cl, 5.41; N, 12.83; O, 12.21
The following data is based on the product molecular weight 655.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
