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MedKoo Cat#: 573692 | Name: Aloe-emodin-glucoside

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aloe-emodin-glucoside is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds.

Chemical Structure

Aloe-emodin-glucoside
Aloe-emodin-glucoside
CAS#29010-56-8

Theoretical Analysis

MedKoo Cat#: 573692

Name: Aloe-emodin-glucoside

CAS#: 29010-56-8

Chemical Formula: C21H20O10

Exact Mass: 432.1056

Molecular Weight: 432.38

Elemental Analysis: C, 58.34; H, 4.66; O, 37.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aloe-emodin-glucoside
IUPAC/Chemical Name
9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-, mono-beta-D-glucopyranoside
InChi Key
ASQHVCDULHERIH-JNHRPPPUSA-N
InChi Code
1S/C21H20O10/c22-6-13-17(26)19(28)20(29)21(31-13)30-7-8-4-10-15(12(24)5-8)18(27)14-9(16(10)25)2-1-3-11(14)23/h1-5,13,17,19-24,26,28-29H,6-7H2/t13-,17-,19+,20-,21-/m1/s1
SMILES Code
c1(cc(cc2C(c3cccc(c3C(c12)=O)O)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kai M, Hayashi K, Kaida I, Aki H, Yamamoto M. Permeation-enhancing effect of aloe-emodin anthrone on water-soluble and poorly permeable compounds in rat colonic mucosa. Biol Pharm Bull. 2002 Dec;25(12):1608-13. PubMed PMID: 12499649. 2: Yagi T, Yamauchi K, Kuwano S. The synergistic purgative action of aloe-emodin anthrone and rhein anthrone in mice: synergism in large intestinal propulsion and water secretion. J Pharm Pharmacol. 1997 Jan;49(1):22-5. PubMed PMID: 9120764. 3: Che QM, Akao T, Hattori M, Kobashi K, Namba T. Isolation of a human intestinal bacterium capable of transforming barbaloin to aloe-emodin anthrone. Planta Med. 1991 Feb;57(1):15-9. PubMed PMID: 2062951.