MedKoo Cat#: 573657 | Name: Aligeron

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aligeron is a cinnarizine analog with antagonistic action against different smooth muscle stimuli.

Chemical Structure

Aligeron
Aligeron
CAS#70713-45-0

Theoretical Analysis

MedKoo Cat#: 573657

Name: Aligeron

CAS#: 70713-45-0

Chemical Formula: C20H26Cl2N2

Exact Mass: 364.1473

Molecular Weight: 365.34

Elemental Analysis: C, 65.75; H, 7.17; Cl, 19.41; N, 7.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Aligeron
IUPAC/Chemical Name
1-(Diphenylmethyl)-4-(2-propenyl)piperazine, dihydrochloride
InChi Key
QWGCFVBATALVAQ-UHFFFAOYSA-N
InChi Code
1S/C20H24N2/c1-2-13-21-14-16-22(17-15-21)20(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h2-12,20H,1,13-17H2
SMILES Code
N1(CCN(CC1)CC=C)C(c1ccccc1)c1ccccc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 365.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Miyares K, Delfin M, Nikolov R, Nikolova M. Antagonistic activity of aligeron and papaverine against different smooth muscle stimuli. Methods Find Exp Clin Pharmacol. 1985 Sep;7(9):473-6. PubMed PMID: 4079597. 2: Nikolov R, Rakovska A, Dushkova R, Dimitrova L, Pavlidu A. Study on the prostaglandin antagonistic activity of aligeron and piracetam. Methods Find Exp Clin Pharmacol. 1982 Aug-Sep;4(6):387-95. PubMed PMID: 6958951. 3: Nikolova M, Nikolov R, Hadjiev D, Yancheva S. Effect of aligeron on the cerebral venous outflow and cerebrospinal fluid pressure in dogs. Methods Find Exp Clin Pharmacol. 1981 Jul-Aug;3(4):213-6. PubMed PMID: 7278433.