Osteosarcoma-IN-D15 | Osteosarcoma Cells Inhibitor

MedKoo Cat#: 565351 | Name: Osteosarcoma-IN-D15

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Osteosarcoma-IN-D15 is an inhibitor of migration and invasion of osteosarcoma cells mediated by p53, regulating EMT-related genes.

Chemical Structure

Osteosarcoma-IN-D15

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 565351

Name: Osteosarcoma-IN-D15

CAS#: NONE

Chemical Formula: C20H17NO

Exact Mass: 287.1310

Molecular Weight: 287.36

Elemental Analysis: C, 83.59; H, 5.96; N, 4.87; O, 5.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Osteosarcoma IN-D15; Osteosarcoma-IN D15; Osteosarcoma-IN-D15

IUPAC/Chemical Name

(E)-1-(4-aminophenyl)-3-(4-methylnaphthalen-1-yl)prop-2-en-1-one

InChi Key

OJOYQEDRRZUUMP-JLHYYAGUSA-N

InChi Code

InChI=1S/C20H17NO/c1-14-6-7-15(19-5-3-2-4-18(14)19)10-13-20(22)16-8-11-17(21)12-9-16/h2-13H,21H2,1H3/b13-10+

SMILES Code

NC1=CC=C(C(/C=C/C2=CC=C(C)C3=C2C=CC=C3)=O)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 287.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Seba V, Silva G, Santos MBD, Baek SJ, França SC, Fachin AL, Regasini LO, Marins M. Chalcone Derivatives 4'-Amino-1-Naphthyl-Chalcone (D14) and 4'-Amino-4-Methyl-1-Naphthyl-Chalcone (D15) Suppress Migration and Invasion of Osteosarcoma Cells Mediated by p53 Regulating EMT-Related Genes. Int J Mol Sci. 2018 Sep 19;19(9). pii: E2838. doi: 10.3390/ijms19092838. PubMed PMID: 30235848; PubMed Central PMCID: PMC6163733.