Synonym
1,3-Didecanoylglycerol; 1,3-Dicaprin; 1,3-Didecanoin; (3-decanoyloxy-2-hydroxypropyl) decanoate; 1,3-Didecanoate-Glycerol.
IUPAC/Chemical Name
Decanoic acid, 2-hydroxy-1,3-propanediyl ester
InChi Key
BPYWNJQNVNYQSQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H44O5/c1-3-5-7-9-11-13-15-17-22(25)27-19-21(24)20-28-23(26)18-16-14-12-10-8-6-4-2/h21,24H,3-20H2,1-2H3
SMILES Code
OC(COC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
400.60
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Smart RC, Huang MT, Conney AH. sn-1,2-Diacylglycerols mimic the effects of 12-O-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis. 1986 Nov;7(11):1865-70. PubMed PMID: 3769135.
7: Watson SP, Reep B, McConnell RT, Lapetina EG. Collagen stimulates [3H]inositol trisphosphate formation in indomethacin-treated human platelets. Biochem J. 1985 Mar 15;226(3):831-7. PubMed PMID: 3872656; PubMed Central PMCID: PMC1144783.
8: Gargouri Y, Pieroni G, Rivière C, Sugihara A, Sarda L, Verger R. Inhibition of lipases by proteins. A kinetic study with dicaprin monolayers. J Biol Chem. 1985 Feb 25;260(4):2268-73. PubMed PMID: 4038705.
9: Momsen WE, Brockman HL. The adsorption to and hydrolysis of 1,3-didecanoyl glycerol monolayers by pancreatic lipase. Effects of substrate packing density. J Biol Chem. 1981 Jul 10;256(13):6913-6. PubMed PMID: 7240252.
10: Dervichian DG, Barque JP. Enzyme-substrate interaction in lipid monolayers. I. Experimental conditions and fundamental kinetics. J Lipid Res. 1979 May;20(4):437-46. PubMed PMID: 458266.
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