MedKoo Cat#: 565306 | Name: VIS351

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VIS351 is the first potent activator of the ITIM-mediated function of the IDO1 enzyme.

Chemical Structure

VIS351
VIS351
CAS#397882-20-1

Theoretical Analysis

MedKoo Cat#: 565306

Name: VIS351

CAS#: 397882-20-1

Chemical Formula: C19H22N2O

Exact Mass: 294.1732

Molecular Weight: 294.40

Elemental Analysis: C, 77.52; H, 7.53; N, 9.52; O, 5.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
VIS351; VIS 351; VIS-351
IUPAC/Chemical Name
1-(2,3-Dimethyl-1H-indol-1-yl)-3-(phenylamino)propan-2-ol
InChi Key
PAJRUSOEFAOLLP-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H22N2O/c1-14-15(2)21(19-11-7-6-10-18(14)19)13-17(22)12-20-16-8-4-3-5-9-16/h3-11,17,20,22H,12-13H2,1-2H3
SMILES Code
PAJRUSOEFAOLLP-UHFFFAOYSA-N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Albini E, Coletti A, Greco F, Pallotta MT, Mondanelli G, Gargaro M, Belladonna ML, Volpi C, Bianchi R, Grohmann U, Macchiarulo A, Orabona C. Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1. Biochem Pharmacol. 2018 Dec;158:286-297. doi: 10.1016/j.bcp.2018.10.033. Epub 2018 Nov 1. PubMed PMID: 30391205.