Cubebin | CAS# 18423-69-3 | Lignan

MedKoo Cat#: 573604 | Name: Cubebin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cubebin is a lignan with anti-inflammatory and neuroprotective effects.

Chemical Structure

Cubebin

CAS#18423-69-3

Theoretical Analysis

MedKoo Cat#: 573604

Name: Cubebin

CAS#: 18423-69-3

Chemical Formula: C20H20O6

Exact Mass: 356.1260

Molecular Weight: 356.37

Elemental Analysis: C, 67.41; H, 5.66; O, 26.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

AI3-62265, Cubebin

IUPAC/Chemical Name

2-Furanol, 3,4-bis(1,3-benzodioxol-5-ylmethyl)tetrahydro-

InChi Key

DIYWRNLYKJKHAM-MDOVXXIYSA-N

InChi Code

1S/C20H20O6/c21-20-15(6-13-2-4-17-19(8-13)26-11-24-17)14(9-22-20)5-12-1-3-16-18(7-12)25-10-23-16/h1-4,7-8,14-15,20-21H,5-6,9-11H2/t14-,15+,20-/m0/s1

SMILES Code

c12ccc(cc2OCO1)C[C@@H]1[C@@H](Cc2cc3c(cc2)OCO3)[C@H](OC1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Melting Point: 131.5 deg C (Source: Experimental)

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 356.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Somani GS, Nahire MS, Parikh AD, Mulik MB, Ghumatkar PJ, Laddha KS, Sathaye S. Neuroprotective effect of Cubebin: A dibenzylbutyrolactone lignan on scopolamine-induced amnesia in mice. Indian J Med Res. 2017 Aug;146(2):255-259. doi: 10.4103/ijmr.IJMR_156_14. PubMed PMID: 29265027; PubMed Central PMCID: PMC5761036. 2: Lima TC, Lucarini R, Volpe AC, de Andrade CQJ, Souza AMP, Pauletti PM, Januário AH, Símaro GV, Bastos JK, Cunha WR, Borges A, da Silva Laurentiz R, Conforti VA, Parreira RLT, Borges CHG, Caramori GF, Andriani KF, E Silva MLA. In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin. Bioorg Med Chem Lett. 2017 Jan 15;27(2):176-179. doi: 10.1016/j.bmcl.2016.11.081. Epub 2016 Nov 29. PubMed PMID: 27955811.