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MedKoo Cat#: 573591 | Name: Orazamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Orazamide is a therapeutic drug that may be useful in the treatment of chronic hepatitis and various skin diseases.

Chemical Structure

Orazamide
Orazamide
CAS#2574-78-9

Theoretical Analysis

MedKoo Cat#: 573591

Name: Orazamide

CAS#: 2574-78-9

Chemical Formula: C9H14N6O7

Exact Mass: 318.0924

Molecular Weight: 318.25

Elemental Analysis: C, 33.97; H, 4.43; N, 26.41; O, 35.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aica orotate dihydrate, Aicamin dihydrate, Aicorat dihydrate, Orazamide, Orazamide dihydrate
IUPAC/Chemical Name
1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid, compoundwith 5-amino-1H-imidazole-4-carboxamide (1:1) dihydrate
InChi Key
PVCSUEOGEIOUHG-UHFFFAOYSA-N
InChi Code
1S/C5H4N2O4.C4H6N4O/c8-3-1-2(4(9)10)6-5(11)7-3;5-3-2(4(6)9)7-1-8-3/h1H,(H,9,10)(H2,6,7,8,11);1H,5H2,(H2,6,9)(H,7,8)
SMILES Code
NC(=O)c1nc[nH]c1N.OC(=O)C2=CC(=O)NC(=O)N2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen X, Jing J, Ren W, Han DE, Jing N, Wang G. Determination of 5-aminoimidazole-4-carboxamide in human plasma by ion-pair extraction and LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Aug 15;855(2):140-4. Epub 2007 May 10. PubMed PMID: 17561451. 2: Pár A, Paál M, Kádas I, Nagy I, Kerekes E, Jávor T. Experiences with Catergen treatment in chronic active hepatitis. Ther Hung. 1983;31(3):105-14. PubMed PMID: 6400472. 3: Roda E, Sama C, Festi D. [Controlled clinical evaluation of the therapeutic effectiveness of AICA orotate in chronic hepatitis]. Clin Ter. 1979 Jun 15;89(5):489-93. Italian. PubMed PMID: 535326. 4: MIYAZAWA T, KUMASAKA S. [THE PHARMACOLOGICAL ACTIVITY OF AICA OROTATE IN VARIOUS SKIN DISEASES]. Hifuka Kiyo. 1965 Feb;60:76-84. Japanese. PubMed PMID: 14286713.