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MedKoo Cat#: 584936 | Name: Orf 17578

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Orf 17578 is a histamine H2-receptor antagonist.

Chemical Structure

Orf 17578
Orf 17578
CAS#75438-42-5

Theoretical Analysis

MedKoo Cat#: 584936

Name: Orf 17578

CAS#: 75438-42-5

Chemical Formula: C15H22N4O3S

Exact Mass: 338.1413

Molecular Weight: 338.43

Elemental Analysis: C, 53.24; H, 6.55; N, 16.56; O, 14.18; S, 9.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Orf 17578; Orf-17578; Orf17578
IUPAC/Chemical Name
1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-2-nitro-N'-2-propynyl-
InChi Key
SMOHSULBMKXDEN-RVDMUPIBSA-N
InChi Code
InChI=1S/C15H22N4O3S/c1-4-7-16-15(11-19(20)21)17-8-9-23-12-14-6-5-13(22-14)10-18(2)3/h1,5-6,11,16-17H,7-10,12H2,2-3H3/b15-11+
SMILES Code
C#CCN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 338.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Katz LB, Scott CK, Shriver DA. Pharmacology of ORF 17578, a new histamine H2-receptor antagonist: comparison with cimetidine and ranitidine. J Pharmacol Exp Ther. 1986 May;237(2):404-10. PubMed PMID: 2871172. 2: Kosh JW, Sowell JW, Chapman JM. A comparison of the cholinergic activity of selected H2-antagonists and sulfoxide metabolites. Pharm Res. 1989 Aug;6(8):709-13. PubMed PMID: 2573049. 3: Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar;29(3):285-90. PubMed PMID: 1970132.