Phosphonic acid, P-decyl- | 6874-60-8

MedKoo Cat#: 581861 | Name: Phosphonic acid, P-decyl-

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phosphonic acid, P-decyl- is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used in stabilizing dye-sensitized solar cell.

Chemical Structure

Phosphonic acid, P-decyl-

CAS#6874-60-8

Theoretical Analysis

MedKoo Cat#: 581861

Name: Phosphonic acid, P-decyl-

CAS#: 6874-60-8

Chemical Formula: C10H23O3P

Exact Mass: 222.1385

Molecular Weight: 222.26

Elemental Analysis: C, 54.04; H, 10.43; O, 21.59; P, 13.94

Price and Availability

Size	Price	Availability	Quantity
1g	USD 230.00
5g	USD 440.00

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Synonym

Phosphonic acid, P-decyl-; 1-Decanephosphonic acid; Decanephosphonic acid; Decylphosphonic acid.

IUPAC/Chemical Name

decylphosphonic acid

InChi Key

DZQISOJKASMITI-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H23O3P/c1-2-3-4-5-6-7-8-9-10-14(11,12)13/h2-10H2,1H3,(H2,11,12,13)

SMILES Code

O=P(O)(O)CCCCCCCCCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

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Product Data

Product Data

Instruction

View handling instruction

Biological target:

Phosphonic acid, P-decyl- is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

In vitro activity:

This work reports an amphiphilic molecular hole transporter, (2-(4-(bis(4-methoxyphenyl)amino)phenyl)-1-cyanovinyl)phosphonic acid, that features a multifunctional cyanovinyl phosphonic acid group and forms a superwetting underlayer for perovskite deposition, which enables high-quality perovskite films with minimized defects at the buried interface. The resulting perovskite film has a photoluminescence quantum yield of 17% and a Shockley-Read-Hall lifetime of nearly 7 microseconds and achieved a certified power conversion efficiency (PCE) of 25.4% with an open-circuit voltage of 1.21 volts and a fill factor of 84.7%. Reference: Science. 2023 Apr 28;380(6643):404-409. https://pubmed.ncbi.nlm.nih.gov/37104579/

In vivo activity:

VLA-4-targeted PET/CT was performed 24 h after intravenous injection of a 64Cu-labeled high-affinity peptidomimetic ligand referred to as 64Cu-LLP2A, which is conjugated with the chelator (1,4,8,11-tetraazacyclotetradecane-1-(methane phosphonic acid)-8-(methane carboxylic acid) and a polyethylene glycol 4 linker, at day 2 after the induction of ALI. Intratracheal lipopolysaccharide instillation led to an acute inflammatory response in the mouse lungs, characterized by increased expression of multiple inflammatory markers and infiltration of myeloid cells, along with a significant and specific increase in 64Cu-LLP2A uptake, predominantly in a peribronchial distribution. There was a strong correlation between the lipopolysaccharide dose and 64Cu-LLP2A uptake, as quantified by in vivo PET (R = 0.69, P < 0.01). Notably, in vivo 64Cu-LLP2A uptake significantly correlated with the expression of multiple inflammatory markers and VLA-4. Reference: J Nucl Med. 2021 Feb;62(2):280-286. https://pubmed.ncbi.nlm.nih.gov/32680928/

Preparing Stock Solutions

The following data is based on the product molecular weight 222.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

1. Zhang S, Ye F, Wang X, Chen R, Zhang H, Zhan L, Jiang X, Li Y, Ji X, Liu S, Yu M, Yu F, Zhang Y, Wu R, Liu Z, Ning Z, Neher D, Han L, Lin Y, Tian H, Chen W, Stolterfoht M, Zhang L, Zhu WH, Wu Y. Minimizing buried interfacial defects for efficient inverted perovskite solar cells. Science. 2023 Apr 28;380(6643):404-409. doi: 10.1126/science.adg3755. Epub 2023 Apr 27. PMID: 37104579. 2. Wang W, Wei K, Yang L, Deng J, Zhang J, Tang W. Dynamic self-assembly of small molecules enables the spontaneous fabrication of hole conductors at perovskite/electrode interfaces for over 22% stable inverted perovskite solar cells. Mater Horiz. 2023 Apr 25. doi: 10.1039/d3mh00219e. Epub ahead of print. PMID: 37097145. 3. Haddad J, Latoche JD, Nigam S, Bellavia MC, Day KE, Zhu Q, Edwards WB, Anderson CJ, Tavakoli S. Molecular Imaging of Very Late Antigen-4 in Acute Lung Injury. J Nucl Med. 2021 Feb;62(2):280-286. doi: 10.2967/jnumed.120.242347. Epub 2020 Jul 17. PMID: 32680928; PMCID: PMC9364870. 4. Kuznetsova INKSO. Study of influence of 1,3-oxazole-4-yl-phosphonic acid derivative on nitric oxide system indicators in rats with arterial hypertension. Ceska Slov Farm. 2018 Winter;67(4):154-159. English. PMID: 30646729.

In vitro protocol:

In vivo protocol:

1. Haddad J, Latoche JD, Nigam S, Bellavia MC, Day KE, Zhu Q, Edwards WB, Anderson CJ, Tavakoli S. Molecular Imaging of Very Late Antigen-4 in Acute Lung Injury. J Nucl Med. 2021 Feb;62(2):280-286. doi: 10.2967/jnumed.120.242347. Epub 2020 Jul 17. PMID: 32680928; PMCID: PMC9364870. 2. Kuznetsova INKSO. Study of influence of 1,3-oxazole-4-yl-phosphonic acid derivative on nitric oxide system indicators in rats with arterial hypertension. Ceska Slov Farm. 2018 Winter;67(4):154-159. English. PMID: 30646729.

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