MedKoo Cat#: 565256 | Name: ASR352

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASR352 is a potent anticancer agent which inhibits the growth of CRC bulk and sensitized FOLFOX-resistant cells.

Chemical Structure

ASR352
ASR352
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 565256

Name: ASR352

CAS#: NONE

Chemical Formula: C16H23ClN4

Exact Mass:

Molecular Weight: 306.84

Elemental Analysis: C, 62.63; H, 7.56; Cl, 11.55; N, 18.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
ASR352; ASR 352; ASR-352
IUPAC/Chemical Name
1-(4-Phenylbut-2-en-1-yl)-1,3,5,7-tetraazaadamantan-1-ium Chloride
InChi Key
GUCREOFDXCCXNF-FXRZFVDSSA-M
InChi Code
InChI=1S/C16H23N4.ClH/c1-2-6-16(7-3-1)8-4-5-9-20-13-17-10-18(14-20)12-19(11-17)15-20;/h1-7H,8-15H2;1H/q+1;/p-1/b5-4+;
SMILES Code
N12C[N+]3(C/C=C/CC4=CC=CC=C4)CN(C2)CN(C3)C1.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 306.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Narayan S, Ramisetti S, Jaiswal AS, Law BK, Singh-Pillay A, Singh P, Amin S, Sharma AK. ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells. Eur J Med Chem. 2019 Jan 1;161:456-467. doi: 10.1016/j.ejmech.2018.10.052. Epub 2018 Oct 23. PubMed PMID: 30384048.