MedKoo Cat#: 565235 | Name: Gentamicin X2 Sulfate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gentamicin X2 Sulfate is a potent premature stop codon readthrough molecule and the common precursor of the gentamicin C antibiotic complex.

Chemical Structure

Gentamicin X2 Sulfate
Gentamicin X2 Sulfate
CAS#57793-88-1

Theoretical Analysis

MedKoo Cat#: 565235

Name: Gentamicin X2 Sulfate

CAS#: 57793-88-1

Chemical Formula: C19H40N4O14S

Exact Mass: 0.0000

Molecular Weight: 580.60

Elemental Analysis: C, 39.31; H, 6.94; N, 9.65; O, 38.58; S, 5.52

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Synonym
Gentamicin X2 Sulfate
IUPAC/Chemical Name
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol Sulfate
InChi Key
WRDONMCALIGOQR-NJWRRGAYSA-N
InChi Code
InChI=1S/C19H38N4O10.H2O4S/c1-19(29)5-30-18(13(28)16(19)23-2)33-15-7(21)3-6(20)14(12(15)27)32-17-9(22)11(26)10(25)8(4-24)31-17;1-5(2,3)4/h6-18,23-29H,3-5,20-22H2,1-2H3;(H2,1,2,3,4)/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m0./s1
SMILES Code
O[C@H]1[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](N)C[C@H]2N)OC[C@@](O)(C)[C@@H]1NC.O=S(O)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Gentamicin X2 Sulfate is a potent premature stop codon readthrough molecule and the common precursor of the gentamicin C antibiotic complex.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 580.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Maleki Dizaj S, Lotfipour F, Barzegar-Jalali M, Zarrintan MH, Adibkia K. Application of Box-Behnken design to prepare gentamicin-loaded calcium carbonate nanoparticles. Artif Cells Nanomed Biotechnol. 2016 Sep;44(6):1475-81. doi: 10.3109/21691401.2015.1042108. Epub 2015 May 7. PubMed PMID: 25950955.