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MedKoo Cat#: 584913 | Name: Ono 11006

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ono 11006 is a thromboxane agonist that dose dependently reduced the positive inotropic effect induced by field stimulation.

Chemical Structure

Ono 11006
Ono 11006
CAS#73509-46-3

Theoretical Analysis

MedKoo Cat#: 584913

Name: Ono 11006

CAS#: 73509-46-3

Chemical Formula: C22H36O3

Exact Mass: 348.2664

Molecular Weight: 348.53

Elemental Analysis: C, 75.82; H, 10.41; O, 13.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ono 11006; Ono-11006; Ono11006
IUPAC/Chemical Name
5-Heptenoic acid, 7-(3-(3-hydroxy-1-octenyl)bicyclo(3.1.1)hept-2-yl)-, (2alpha(Z),3beta(1E,3S*))-(+-)-
InChi Key
ZIWNJZLXPXFNGN-KLWJVMJQSA-N
InChi Code
InChI=1S/C22H36O3/c1-2-3-6-9-20(23)13-12-18-14-17-15-19(16-17)21(18)10-7-4-5-8-11-22(24)25/h4,7,12-13,17-21,23H,2-3,5-6,8-11,14-16H2,1H3,(H,24,25)/b7-4-,13-12+/t17?,18-,19?,20?,21-/m1/s1
SMILES Code
O=C(O)CCC/C=C\C[C@H]1C(C2)CC2C[C@H]1/C=C/C(O)CCCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 348.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mantelli L, Amerini S, Rubino A, Ledda F. Effects of thromboxane agonists on cardiac adrenergic neurotransmission. Eur J Pharmacol. 1992 Mar 17;213(1):79-85. PubMed PMID: 1323473. 2: Nakahata N, Takano H, Ohizumi Y. Thromboxane A2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles. Life Sci. 2000;66(5):PL 71-6. PubMed PMID: 10670835.