CA140 | Neuroinflammatory Response Inhbitor

MedKoo Cat#: 565196 | Name: CA140

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CA140 is an inhibitor of the neuroinflammatory response in wild-type mice and a mouse model of Alzheimer's disease (AD).

Chemical Structure

CA140

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 565196

Name: CA140

CAS#: NONE

Chemical Formula: C16H18N2O3

Exact Mass: 286.1317

Molecular Weight: 286.33

Elemental Analysis: C, 67.12; H, 6.34; N, 9.78; O, 16.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Non-self-polymerizing analog of dopamine (DA); CA-140; CA 140; CA140

IUPAC/Chemical Name

N-(3,4-Dihydroxyphenethyl)-2-(methylamino)benzamide

InChi Key

UQPZVGMQOFXKPE-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H18N2O3/c1-17-13-5-3-2-4-12(13)16(21)18-9-8-11-6-7-14(19)15(20)10-11/h2-7,10,17,19-20H,8-9H2,1H3,(H,18,21)

SMILES Code

O=C(NCCC1=CC=C(O)C(O)=C1)C2=CC=CC=C2NC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 286.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lee JY, Nam JH, Nam Y, Nam HY, Yoon G, Ko E, Kim SB, Bautista MR, Capule CC, Koyanagi T, Leriche G, Choi HG, Yang J, Kim J, Hoe HS. The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD. J Neuroinflammation. 2018 Oct 11;15(1):286. doi: 10.1186/s12974-018-1321-3. PubMed PMID: 30309372; PubMed Central PMCID: PMC6182807.