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MedKoo Cat#: 565173 | Name: HJ-PI01

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HJ-PI01 is a Pim-2 inhibitor which induces apoptosis and autophagic cell death in triple-negative human breast cancer.

Chemical Structure

HJ-PI01
HJ-PI01
CAS#6192-43-4

Theoretical Analysis

MedKoo Cat#: 565173

Name: HJ-PI01

CAS#: 6192-43-4

Chemical Formula: C14H11NO2

Exact Mass: 225.0790

Molecular Weight: 225.25

Elemental Analysis: C, 74.65; H, 4.92; N, 6.22; O, 14.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HJPI01; HJ-PI01; HJ PI01
IUPAC/Chemical Name
N-Acetylphenoxazine; 1-(10H-Phenoxazin-10-yl)ethan-1-one
InChi Key
MXVOQCUXOQFIHU-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H11NO2/c1-10(16)15-11-6-2-4-8-13(11)17-14-9-5-3-7-12(14)15/h2-9H,1H3
SMILES Code
O=C(N1C2=C(C=CC=C2)OC3=CC=CC=C13)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 225.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhao YQ, Yin YQ, Liu J, Wang GH, Huang J, Zhu LJ, Wang JH. Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50. doi: 10.1038/aps.2016.60. Epub 2016 Jul 11. PubMed PMID: 27397540; PubMed Central PMCID: PMC5022099.