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MedKoo Cat#: 573524 | Name: AO-1535

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AO-1535 is a semisynthetic monoglycosylceramide derived from O-glycosilated sphingosine. It has been shown to inhibit superoxide production by macrophages suggesting a potential clinical application of AO 1535 in the treatment of inflammatory dermatoses.

Chemical Structure

AO-1535
AO-1535
CAS#87178-48-1

Theoretical Analysis

MedKoo Cat#: 573524

Name: AO-1535

CAS#: 87178-48-1

Chemical Formula: C30H50N2O8

Exact Mass: 566.3567

Molecular Weight: 566.74

Elemental Analysis: C, 63.58; H, 8.89; N, 4.94; O, 22.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AO-1535, AO1535, AO 1535
IUPAC/Chemical Name
3-Pyridinecarboxamide, N-(1-((beta-D-galactopyranosyloxy)methyl)-2-hydroxy-3-heptadecenyl)-, (R-(R*,S*-(E)))-
InChi Key
FZKMNTGJBCFURC-LBCQLIQWSA-N
InChi Code
1S/C30H50N2O8/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-24(34)23(32-29(38)22-16-15-18-31-19-22)21-39-30-28(37)27(36)26(35)25(20-33)40-30/h14-19,23-28,30,33-37H,2-13,20-21H2,1H3,(H,32,38)/b17-14+/t23-,24+,25+,26-,27-,28+,30+/m0/s1
SMILES Code
c1c(cccn1)C(=O)N[C@H]([C@@H](\C=C\CCCCCCCCCCCCC)O)CO[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O1)CO
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 566.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Spampinato G, Messina L, Malaguarnera L, Arcidiacono A, Giuffrida MA, Guarniera E, Geremia E, Rastrelli A, Messina A. AO 1535 inhibits O2- production by human macrophages. Immunopharmacology. 1992 Jul-Aug;24(1):25-30. PubMed PMID: 1333456.