MedKoo Cat#: 565167 | Name: HMNQ

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HMNQ is a natural quinolone which acts synergistically with HQNO to inhibit bacterial growth by targeting distinct steps in energy production, as well as by inhibiting pyrimidine biosynthesis.

Chemical Structure

HMNQ
HMNQ
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 565167

Name: HMNQ

CAS#: NONE

Chemical Formula: C19H25NO

Exact Mass: 283.1936

Molecular Weight: 283.42

Elemental Analysis: C, 80.52; H, 8.89; N, 4.94; O, 5.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HMNQ
IUPAC/Chemical Name
(E)-3-Methyl-2-(non-2-en-1-yl)quinolin-4(1H)-one
InChi Key
XICKFFMQHHMRFO-CMDGGOBGSA-N
InChi Code
InChI=1S/C19H25NO/c1-3-4-5-6-7-8-9-13-17-15(2)19(21)16-12-10-11-14-18(16)20-17/h8-12,14H,3-7,13H2,1-2H3,(H,20,21)/b9-8+
SMILES Code
O=C1C(C)=C(C/C=C/CCCCCC)NC2=C1C=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lee EB, Cheon MG, Cui J, Lee YJ, Seo EK, Jang HH. The quinone-based derivative, HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells. Oncotarget. 2017 Sep 18;8(59):99637-99648. doi: 10.18632/oncotarget.21005. eCollection 2017 Nov 21. PubMed PMID: 29245930; PubMed Central PMCID: PMC5725121.