DEBIC | Venous Thrombosis Inhibitor

MedKoo Cat#: 565166 | Name: DEBIC

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DEBIC is an inhibitor of venous thrombosis which induces no bleeding side effect.

Chemical Structure

DEBIC

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 565166

Name: DEBIC

CAS#: NONE

Chemical Formula: C22H20N2O4

Exact Mass: 376.1423

Molecular Weight: 376.41

Elemental Analysis: C, 70.20; H, 5.36; N, 7.44; O, 17.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

DEBIC

IUPAC/Chemical Name

Dimethyl 2,2'-(ethane-1,1-diyl)bis(1H-indole-3-carboxylate)

InChi Key

BONKEFIIFQRBDD-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H20N2O4/c1-12(19-17(21(25)27-2)13-8-4-6-10-15(13)23-19)20-18(22(26)28-3)14-9-5-7-11-16(14)24-20/h4-12,23-24H,1-3H3

SMILES Code

CC(C(N1)=C(C(OC)=O)C2=C1C=CC=C2)C(N3)=C(C(OC)=O)C4=C3C=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 376.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang Y, Chen H, Zhang X, Gui L, Wu J, Feng Q, Peng S, Zhao M. Dimethyl 2,2'-[2,2'-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect. Int J Nanomedicine. 2018 Nov 22;13:7835-7844. doi: 10.2147/IJN.S178683. eCollection 2018. PubMed PMID: 30538462; PubMed Central PMCID: PMC6254983. 2: Chen H, Wang W, Zhang X, Liu S, Wang Y, Zhu H, Wu J, Wang Y, Zhao M, Peng S. Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis. Oncotarget. 2017 Dec 8;9(63):32119-32133. doi: 10.18632/oncotarget.23151. eCollection 2018 Aug 14. PubMed PMID: 30181803; PubMed Central PMCID: PMC6114953.