MedKoo Cat#: 565139 | Name: BC-11 hydrobromide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BC-11 hydrobromide is an inhibitor of Urokinase-Plasminogen Activator (uPa) which induces additional impairment of mitochondrial activity, the production of reactive oxygen species, and promotion of apoptosis.

Chemical Structure

BC-11 hydrobromide
BC-11 hydrobromide
CAS#443776-49-6

Theoretical Analysis

MedKoo Cat#: 565139

Name: BC-11 hydrobromide

CAS#: 443776-49-6

Chemical Formula: C8H12BBrN2O2S

Exact Mass: 289.9896

Molecular Weight: 290.97

Elemental Analysis: C, 33.02; H, 4.16; B, 3.72; Br, 27.46; N, 9.63; O, 11.00; S, 11.02

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
BC11 hydrobromide; BC-11 hydrobromide; BC 11 hydrobromide; BC-11 HBr
IUPAC/Chemical Name
(4-((Carbamimidoylthio)methyl)phenyl)boronic acid hydrobromide
InChi Key
PAFZAMOVHIRQOD-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H
SMILES Code
NC(SCC1=CC=C(B(O)O)C=C1)=N.[H]Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Longo A, Librizzi M, Chuckowree IS, Baltus CB, Spencer J, Luparello C. Cytotoxicity of the Urokinase-Plasminogen Activator Inhibitor Carbamimidothioic Acid (4-Boronophenyl) Methyl Ester Hydrobromide (BC-11) on Triple-Negative MDA-MB231 Breast Cancer Cells. Molecules. 2015 May 28;20(6):9879-89. doi: 10.3390/molecules20069879. PubMed PMID: 26029857; PubMed Central PMCID: PMC6272237.