MedKoo Cat#: 565134 | Name: LASV-IN-3.3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

LASV-IN-3.3 is a specific inhibitor of Lassa fever virus (LASV) which targets lysosome-associated membrane protein 1 (LAMP1), which is a host factor that binds to the LASV glycoprotein (GP) during infection.

Chemical Structure

LASV-IN-3.3
LASV-IN-3.3
CAS#554438-52-7

Theoretical Analysis

MedKoo Cat#: 565134

Name: LASV-IN-3.3

CAS#: 554438-52-7

Chemical Formula: C30H37N3O2

Exact Mass: 471.2886

Molecular Weight: 471.65

Elemental Analysis: C, 76.40; H, 7.91; N, 8.91; O, 6.78

Price and Availability

Size Price Availability Quantity
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 7,450.00 2 Weeks
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Related CAS #
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Synonym
LASV-IN-3.3; LASV-IN 3.3; LASV-IN3.3; LASV-IN-33; LASV-IN 33; LASV-IN33;
IUPAC/Chemical Name
N-(2-(4-Benzhydrylpiperazin-1-yl)-2-oxoethyl)adamantane-1-carboxamide
InChi Key
CUSOKWBOIRFXDP-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H37N3O2/c34-27(21-31-29(35)30-18-22-15-23(19-30)17-24(16-22)20-30)32-11-13-33(14-12-32)28(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-10,22-24,28H,11-21H2,(H,31,35)
SMILES Code
O=C(C12CC3CC(C2)CC(C3)C1)NCC(N4CCN(C(C5=CC=CC=C5)C6=CC=CC=C6)CC4)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 471.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wang MK, Ren T, Liu H, Lim SY, Lee K, Honko A, Zhou H, Dyall J, Hensley L, Gartin AK, Cunningham JM. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322. doi: 10.1371/journal.ppat.1007322. PMID: 30265711; PMCID: PMC6179309.