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MedKoo Cat#: 573475 | Name: AGN-190851

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AGN-190851 is an alpha-2 adrenoceptor agonist which acts as a water diuretic by inhibiting vasopressin-stimulated cyclic AMP accumulation in cortical collecting tubules in mouse models.

Chemical Structure

AGN-190851
AGN-190851
CAS#134892-42-5

Theoretical Analysis

MedKoo Cat#: 573475

Name: AGN-190851

CAS#: 134892-42-5

Chemical Formula: C11H15BrN6

Exact Mass: 310.0542

Molecular Weight: 311.19

Elemental Analysis: C, 42.46; H, 4.86; Br, 25.68; N, 27.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AGN-190851, AGN190851, AGN 190851
IUPAC/Chemical Name
5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl-amino)-1,2,3,4-tetrahydro-6-quinoxalinamine
InChi Key
CETMNKCDAHCKRC-UHFFFAOYSA-N
InChi Code
1S/C11H14BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-2,13-14H,3-6H2,(H2,15,16,17)
SMILES Code
N1CCNc2c(c(ccc12)NC1=NCCN1)Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 311.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brooks DP, Edwards RM, Depalma PD, Fredrickson TA, Hieble JP, Gellai M. The water diuretic effect of the alpha-2 adrenoceptor agonist, AGN 190851, is species-dependent. J Pharmacol Exp Ther. 1991 Dec;259(3):1277-82. PubMed PMID: 1684820.