IUPAC/Chemical Name
Spirostan-2,3,6-triol, (2alpha,3beta,5alpha,6beta,25R)-
InChi Key
FYRLHXNMINIDCB-LEGLVIAUSA-N
InChi Code
1S/C27H44O5/c1-14-5-8-27(31-13-14)15(2)24-23(32-27)11-18-16-9-20(28)19-10-21(29)22(30)12-26(19,4)17(16)6-7-25(18,24)3/h14-24,28-30H,5-13H2,1-4H3/t14-,15+,16-,17+,18+,19-,20-,21-,22-,23+,24+,25+,26-,27-/m1/s1
SMILES Code
C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4C[C@H]([C@@H]6[C@@]5(C[C@H]([C@@H](C6)O)O)C)O)C)C)OC1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
448.64
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Lanzotti V, Barile E, Antignani V, Bonanomi G, Scala F. Antifungal saponins from bulbs of garlic, Allium sativum L. var. Voghiera. Phytochemistry. 2012 Jun;78:126-34. doi: 10.1016/j.phytochem.2012.03.009. Epub 2012 Apr 16. PubMed PMID: 22513009.
2: Tian Y, Sun LM, Liu XQ, Li B, Wang Q, Dong JX. Anti-HBV active flavone glucosides from Euphorbia humifusa Willd. Fitoterapia. 2010 Oct;81(7):799-802. doi: 10.1016/j.fitote.2010.04.012. Epub 2010 May 5. PubMed PMID: 20450964.
3: Carotenuto A, Fattorusso E, Lanzotti V, Magno S, De Feo V, Carnuccio R, D'Acquisto F. Porrigenins A and B, novel cytotoxic and antiproliferative sapogenins isolated from Allium porrum. J Nat Prod. 1997 Oct;60(10):1003-7. PubMed PMID: 9358643.
4: Syrov VN, Kurmukov AG. [Experimental study of the anabolic activity of 6-ketoderivatives of certain natural sapogenins]. Farmakol Toksikol. 1976 Sep-Oct;39(5):631-5. Russian. PubMed PMID: 1028596.
