TUPS | CAS# 950184-27-7 | Epoxide Hydrolase Inhibitor

MedKoo Cat#: 564995 | Name: TUPS

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TUPS is a selective soluble epoxide hydrolase inhibitor which protects against isoprenaline-induced cardiac hypertrophy.

Chemical Structure

TUPS

CAS#950184-27-7

Theoretical Analysis

MedKoo Cat#: 564995

Name: TUPS

CAS#: 950184-27-7

Chemical Formula: C14H18F3N3O4S

Exact Mass: 381.0970

Molecular Weight: 381.37

Elemental Analysis: C, 44.09; H, 4.76; F, 14.94; N, 11.02; O, 16.78; S, 8.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

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Synonym

TUPS

IUPAC/Chemical Name

1-(1-Methanesulfonyl-piperidin-4-yl)-3-(4-trifluoromethoxy-phenyl)-urea

InChi Key

YORLNOBDSZJFQQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H18F3N3O4S/c1-25(22,23)20-8-6-11(7-9-20)19-13(21)18-10-2-4-12(5-3-10)24-14(15,16)17/h2-5,11H,6-9H2,1H3,(H2,18,19,21)

SMILES Code

O=C(NC1=CC=C(OC(F)(F)F)C=C1)NC2CCN(S(=O)(C)=O)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 381.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO. Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy. Br J Pharmacol. 2013 Apr;168(8):1794-807. doi: 10.1111/bph.12066. PubMed PMID: 23176298; PubMed Central PMCID: PMC3623051.