MedKoo Cat#: 564970 | Name: FlAsH-EDT2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FlAsH-EDT2 is a pro-fluorescent, membrane-permeable, covalent CCPGCC targeted probe.

Chemical Structure

FlAsH-EDT2
FlAsH-EDT2
CAS#212118-77-9

Theoretical Analysis

MedKoo Cat#: 564970

Name: FlAsH-EDT2

CAS#: 212118-77-9

Chemical Formula: C24H18As2O5S4

Exact Mass: 663.8469

Molecular Weight: 664.49

Elemental Analysis: C, 43.38; H, 2.73; As, 22.55; O, 12.04; S, 19.30

Price and Availability

Size Price Availability Quantity
5mg USD 385.00 2 Weeks
10mg USD 650.00 2 Weeks
25g USD 1,050.00 2 Weeks
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Synonym
FlAsH-EDT2; FlAsH EDT2; FlAsH-EDT-2; Fluorescein Arsenical Helix Binder; Lumio Green
IUPAC/Chemical Name
4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
InChi Key
AJNUQUGWNQHQDJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H18As2O5S4/c27-17-7-5-15-21(19(17)25-32-9-10-33-25)30-22-16(6-8-18(28)20(22)26-34-11-12-35-26)24(15)14-4-2-1-3-13(14)23(29)31-24/h1-8,27-28H,9-12H2
SMILES Code
O=C1OC2(C3=C(OC4=C2C=CC(O)=C4[As]5SCCS5)C([As]6SCCS6)=C(O)C=C3)C7=C1C=CC=C7
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 664.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Piras L, Avitabile C, D'Andrea LD, Saviano M, Romanelli A. Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT(2). Biochem Biophys Res Commun. 2017 Nov 4;493(1):126-131. doi: 10.1016/j.bbrc.2017.09.064. Epub 2017 Sep 15. PubMed PMID: 28919425. 2: Adams SR, Tsien RY. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34. doi: 10.1038/nprot.2008.144. PubMed PMID: 18772880; PubMed Central PMCID: PMC2843588. 3: Stroffekova K, Proenza C, Beam KG. The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins. Pflugers Arch. 2001 Sep;442(6):859-66. PubMed PMID: 11680618.