MedKoo Cat#: 564966 | Name: 2PyG

Description:

WARNING: This product is for research use only, not for human or veterinary use.

2PyG is a highly fluorescent guanosine mimic for folding and energy transfer studies.

Chemical Structure

2PyG
2PyG
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564966

Name: 2PyG

CAS#: NONE

Chemical Formula: C15H16N6O4

Exact Mass: 344.1233

Molecular Weight: 344.33

Elemental Analysis: C, 52.32; H, 4.68; N, 24.41; O, 18.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
2-PyG; 2 PyG; 2PyG
IUPAC/Chemical Name
8-(2-Pyridyl)-2'-deoxyguanosine
InChi Key
CJWJWSHVISEFOC-IVZWLZJFSA-N
InChi Code
InChI=1S/C15H16N6O4/c16-15-19-13-11(14(24)20-15)18-12(7-3-1-2-4-17-7)21(13)10-5-8(23)9(6-22)25-10/h1-4,8-10,22-23H,5-6H2,(H3,16,19,20,24)/t8-,9+,10+/m0/s1
SMILES Code
OC[C@@H]1[C@H](C[C@H](N2C(C3=NC=CC=C3)=NC4=C2N=C(N)NC4=O)O1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 344.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dumas A, Luedtke NW. Fluorescence properties of 8-(2-pyridyl)guanine "2PyG" as compared to 2-aminopurine in DNA. Chembiochem. 2011 Sep 5;12(13):2044-51. doi: 10.1002/cbic.201100214. Epub 2011 Jul 22. PubMed PMID: 21786378. 2: Dumas A, Luedtke NW. Highly fluorescent guanosine mimics for folding and energy transfer studies. Nucleic Acids Res. 2011 Aug;39(15):6825-34. doi: 10.1093/nar/gkr281. Epub 2011 May 6. PubMed PMID: 21551219; PubMed Central PMCID: PMC3159459.