BSc5371 is a potent FLT3 inhibitor (IC50 = 6.0 nM) with Activity toward Resistance-Conferring Mutations. BSc5371 displays superior cytotoxicity in FLT3-dependent cell lines to compounds in recent clinical trials and overcomes drug-resistant mutations.
MedKoo Cat#: 407980
Name: BSc5371
CAS#: Unknown
Chemical Formula: C24H31N5O4S
Exact Mass: 485.2097
Molecular Weight: 485.60
Elemental Analysis: C, 59.36; H, 6.43; N, 14.42; O, 13.18; S, 6.60
The following data is based on the product molecular weight 485.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
