TTT20171 is a SDHC inhibitor. TTT20171 displays nanomolar inhibition of CII but lacks cellular potency. In cell assays, the most sensitive cells (22Rv1 prostate cancer cells) are inhibited at an IC50=5.4 uM, a value well above the suggested use concentration of 2 uM and the criterion of 1 uM for a quality chemical probe.
MedKoo Cat#: 407978
Name: TTT20171
CAS#: 2110408-47-2
Chemical Formula: C20H33NO5
Exact Mass: 367.2359
Molecular Weight: 367.49
Elemental Analysis: C, 65.37; H, 9.05; N, 3.81; O, 21.77
The following data is based on the product molecular weight 367.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
