AZD-2184 | CAS# 945400-24-8 | Radioligand

MedKoo Cat#: 573393 | Name: AZD-2184

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZD-2184 is a radioligand for detecting beta-amyloid deposits.

Chemical Structure

AZD-2184

CAS#945400-24-8

Theoretical Analysis

MedKoo Cat#: 573393

Name: AZD-2184

CAS#: 945400-24-8

Chemical Formula: C13H11N3OS

Exact Mass: 257.0623

Molecular Weight: 257.31

Elemental Analysis: C, 60.68; H, 4.31; N, 16.33; O, 6.22; S, 12.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AZD-2184, AZD2184, AZD 2184, J2.698.897G

IUPAC/Chemical Name

6-Benzothiazolol, 2-(6-(methylamino)-3-pyridinyl)-

InChi Key

FYTAUNFPOYWHBC-UHFFFAOYSA-N

InChi Code

1S/C13H11N3OS/c1-14-12-5-2-8(7-15-12)13-16-10-4-3-9(17)6-11(10)18-13/h2-7,17H,1H3,(H,14,15)

SMILES Code

CNc1ccc(cn1)c2nc3ccc(O)cc3s2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 257.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kuang G, Murugan NA, Tu Y, Nordberg A, Ågren H. Investigation of the Binding Profiles of AZD2184 and Thioflavin T with Amyloid-β(1-42) Fibril by Molecular Docking and Molecular Dynamics Methods. J Phys Chem B. 2015 Sep 3;119(35):11560-7. doi: 10.1021/acs.jpcb.5b05964. Epub 2015 Aug 24. PubMed PMID: 26266837. 2: Johnson AE, Jeppsson F, Sandell J, Wensbo D, Neelissen JA, Juréus A, Ström P, Norman H, Farde L, Svensson SP. AZD2184: a radioligand for sensitive detection of beta-amyloid deposits. J Neurochem. 2009 Mar;108(5):1177-86. doi: 10.1111/j.1471-4159.2008.05861.x. Epub 2009 Jan 24. PubMed PMID: 19141073.