AZD 3043 | CAS# 579494-66-9 | Sedative Agent

MedKoo Cat#: 573384 | Name: AZD 3043

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent.

Chemical Structure

AZD 3043

CAS#579494-66-9

Theoretical Analysis

MedKoo Cat#: 573384

Name: AZD 3043

CAS#: 579494-66-9

Chemical Formula: C19H29NO5

Exact Mass: 351.2046

Molecular Weight: 351.44

Elemental Analysis: C, 64.93; H, 8.32; N, 3.99; O, 22.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AZD 3043, AZD-3043, AZD3043, THRX 918661

IUPAC/Chemical Name

Benzeneacetic acid, 4-(2-(diethylamino)-2-oxoethoxy)-3-ethoxy-, propyl ester

InChi Key

QPUVKSKJCNGSGT-UHFFFAOYSA-N

InChi Code

S/C19H29NO5/c1-5-11-24-19(22)13-15-9-10-16(17(12-15)23-8-4)25-14-18(21)20(6-2)7-3/h9-10,12H,5-8,11,13-14H2,1-4H3

SMILES Code

CCCOC(=O)Cc1ccc(c(c1)OCC)OCC(=O)N(CC)CC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 351.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang S, Liu Q, Li X, Zhao X, Qiu L, Lin J. Possible binding sites and interactions of propanidid and AZD3043 within the γ-aminobutyric acid type A receptor (GABA(A)R). J Biomol Struct Dyn. 2018 Nov;36(15):3926-3937. doi: 10.1080/07391102.2017.1403959. Epub 2017 Nov 29. PubMed PMID: 29125020. 2: Sear JW, Egan TD. David (Propofol Wannabes) Versus Goliath (Propofol): AZD-3043 Goes Up Against the Giant! Anesth Analg. 2015 Oct;121(4):849-51. doi: 10.1213/ANE.0000000000000904. PubMed PMID: 26378696. 3: Egan TD, Obara S, Jenkins TE, Jaw-Tsai SS, Amagasu S, Cook DR, Steffensen SC, Beattie DT. AZD-3043: a novel, metabolically labile sedative-hypnotic agent with rapid and predictable emergence from hypnosis. Anesthesiology. 2012 Jun;116(6):1267-77. doi: 10.1097/ALN.0b013e31825685a6. PubMed PMID: 22531340; PubMed Central PMCID: PMC4056591.