Azamitosene | CAS# 135513-52-9 | DNA Cleaving Agent

MedKoo Cat#: 573380 | Name: Azamitosene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azamitosene is a DNA cleaving agent exhibiting G and A base specificity. Azamitosene may exhibit a growth inhibitory effect on human gastric cancer cells.

Chemical Structure

Azamitosene

CAS#135513-52-9

Theoretical Analysis

MedKoo Cat#: 573380

Name: Azamitosene

CAS#: 135513-52-9

Chemical Formula: C13H13N3O2

Exact Mass: 243.1008

Molecular Weight: 243.27

Elemental Analysis: C, 64.19; H, 5.39; N, 17.27; O, 13.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Azamitosene

IUPAC/Chemical Name

1H-Pyrrolo(1,2-a)benzimidazole-5,8-dione, 6-(1-aziridinyl)-2,3-dihydro-7-methyl-

InChi Key

JMPIKAIHZHQTPW-UHFFFAOYSA-N

InChi Code

1S/C13H13N3O2/c1-7-10(15-5-6-15)13(18)9-11(12(7)17)16-4-2-3-8(16)14-9/h2-6H2,1H3

SMILES Code

CC1=C(C(=O)c2c(n3c(n2)CCC3)C1=O)N4CC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 243.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kim SK, Ahn CM, Choi SJ, Park YS, Cho HC, Koh CM. The growth inhibitiory effect of new pyrrolo[1,2-alpha]benzimidazole derivatives on human gastric cancer cells. Arch Pharm Res. 1997 Oct;20(5):410-3. doi: 10.1007/BF02973931. PubMed PMID: 18982481. 2: Skibo EB, Schulz WG. Pyrrolo[1,2-a]benzimidazole-based aziridinyl quinones. A new class of DNA cleaving agent exhibiting G and A base specificity. J Med Chem. 1993 Oct 15;36(21):3050-5. PubMed PMID: 8230090.