Selgantolimod, also known as GS-9688, is a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B. Potent TLR8 agonism (IL-12p40 EC50 =220 nM) and >100-fold TLR7 selectivity (IFN-α EC50 > 50 μM) was observed in human peripheral blood mononuclear cells (PBMCs).
MedKoo Cat#: 584818
Name: Selgantolimod
CAS#: 2004677-13-6
Chemical Formula: C14H20FN5O
Exact Mass: 293.1652
Molecular Weight: 293.35
Elemental Analysis: C, 57.32; H, 6.87; F, 6.48; N, 23.87; O, 5.45
The following data is based on the product molecular weight 293.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
