Azetepa | CAS# 125-45-1 | Antineoplastic

MedKoo Cat#: 573375 | Name: Azetepa

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azetepa is an alkylating agent with antineoplastic effects.

Chemical Structure

Azetepa

CAS#125-45-1

Theoretical Analysis

MedKoo Cat#: 573375

Name: Azetepa

CAS#: 125-45-1

Chemical Formula: C8H14N5OPS

Exact Mass: 259.0657

Molecular Weight: 259.27

Elemental Analysis: C, 37.06; H, 5.44; N, 27.01; O, 6.17; P, 11.95; S, 12.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Aza TEPA, Azatep, Azetepa, CL 25477

IUPAC/Chemical Name

Phosphinic amide, P,P-bis(1-aziridinyl)-N-ethyl-N-1,3,4-thiadiazol-2-yl-

InChi Key

HRXVDDOKERXBEY-UHFFFAOYSA-N

InChi Code

1S/C8H14N5OPS/c1-2-13(8-10-9-7-16-8)15(14,11-3-4-11)12-5-6-12/h7H,2-6H2,1H3

SMILES Code

CCN(c1nncs1)P(=O)(N2CC2)N3CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 259.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Choy DS, Arandia J, Rosenbaum I. Clinical evaluation of a new alkylating agent, azetepa, in one hundred and twenty-five cases of malignant tumors. Int J Cancer. 1967 Mar 15;2(2):189-93. PubMed PMID: 6039768. 2: McLean JA. Azetepa--a new alkylating agent. Isr J Med Sci. 1965 Jul;1(4):805-7. PubMed PMID: 5323047. 3: MCLEAN JA. "AZETEPA": A NEW ALKYLATING AGENT. Med J Aust. 1965 Apr 24;1(17):620-3. PubMed PMID: 14293517. 4: FALKSON G, FALKSON HC. AZETEPA (NSC-64826) IN STAGE IV BREAST CANCER. Cancer Chemother Rep. 1964 Dec;43:19-24. PubMed PMID: 14250646. 5: BATEMAN JC. CLINICAL STUDIES WITH AZETEPA IN THE TREATMENT OF ADVANCED CANCER. Acta Unio Int Contra Cancrum. 1964;20:345-51. PubMed PMID: 14155996. 6: CHOY DS, STYLIANOU S. Clinical experience with a new alkylating agent, azetepa, in a variety of solid tumors. Cancer Chemother Rep. 1962 Oct;23:47-50. PubMed PMID: 14021063.