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MedKoo Cat#: 564867 | Name: NY0116

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NY0116 is an agonist of neuromedin U receptor 2 (NMUR2) which decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells.

Chemical Structure

NY0116
NY0116
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564867

Name: NY0116

CAS#: NONE

Chemical Formula: C22H23N3O

Exact Mass: 345.1841

Molecular Weight: 345.45

Elemental Analysis: C, 76.49; H, 6.71; N, 12.16; O, 4.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NY-0116; NY 0116; NY0116
IUPAC/Chemical Name
1-(2-(Trityloxy)ethyl)guanidine
InChi Key
FZXFGYLHTRBHNJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23N3O/c23-21(24)25-16-17-26-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H4,23,24,25)
SMILES Code
NC(NCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 345.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sampson CM, Kasper JM, Felsing DE, Raval SR, Ye N, Wang P, Patrikeev I, Rytting E, Zhou J, Allen JA, Hommel JD. Small-Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models. Pharmacol Res Perspect. 2018 Aug 23;6(5):e00425. doi: 10.1002/prp2.425. eCollection 2018 Oct. PubMed PMID: 30151213; PubMed Central PMCID: PMC6106167.