PF-06745268 is an orally available, brain penetrant, potent and selective γ-secretase modulator. PF-06745268 induces robust and sustained reduction of brain amyloid-β42 (Aβ42) in rats.
MedKoo Cat#: 531345
Name: PF-06745268
CAS#: 1812190-38-7
Chemical Formula: C26H25F3N4O3
Exact Mass: 498.1879
Molecular Weight: 498.51
Elemental Analysis: C, 62.64; H, 5.06; F, 11.43; N, 11.24; O, 9.63
The following data is based on the product molecular weight 498.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
