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MedKoo Cat#: 573352 | Name: AY 25674

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AY 25674 is a drug with antiallergic properties which has been shown to inhibit passive anaphylaxis in rat.

Chemical Structure

AY 25674
AY 25674
CAS#65425-48-1

Theoretical Analysis

MedKoo Cat#: 573352

Name: AY 25674

CAS#: 65425-48-1

Chemical Formula: C11H11NO4

Exact Mass: 221.0688

Molecular Weight: 221.21

Elemental Analysis: C, 59.73; H, 5.01; N, 6.33; O, 28.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AY-25,674, AY 25674
IUPAC/Chemical Name
Acetic acid, oxo((7-oxo-1,3,5-cycloheptatrien-1-yl)amino)-, ethyl ester
InChi Key
CRXULLXPVXXUJL-UHFFFAOYSA-N
InChi Code
1S/C11H11NO4/c1-2-16-11(15)10(14)12-8-6-4-3-5-7-9(8)13/h3-7H,2H2,1H3,(H,12,13,14)
SMILES Code
C(C(Nc1cccccc1=O)=O)(=O)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 221.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pugsley TA, Lippmann W. Effects of [N-(2-oxo-3,5,7-cycloheptatrien-1-yl)] aminooxoacetic acid ethyl ester (AY-25,674) on cyclic 3',5'-nucleotide formation and phosphodiesterase activity. Experientia. 1979 Jan 15;35(1):88-90. PubMed PMID: 217716. 2: Greenberg R, Martel RR, Smorong K. Inhibition of passive lung anaphylaxis in the rat by AY-25,674. Can J Physiol Pharmacol. 1979 Jan;57(1):48-52. PubMed PMID: 106941. 3: Martel PR, Klicius J, Pinski J. Inhibition of passive anaphylaxis induced in the rat hind paw and peritoneal cavity by N-(2-oxo-3,5,7-cycloheptatrien-1-yl)-aminooxoacetic acid ethyl ester (AY-25,674). Can J Physiol Pharmacol. 1978 Dec;56(6):1005-10. PubMed PMID: 743615.