MedKoo Cat#: 564827 | Name: NIR-HS

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NIR-HS is a highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulfide in living cells and in mice.

Chemical Structure

NIR-HS
NIR-HS
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564827

Name: NIR-HS

CAS#: NONE

Chemical Formula: C34H32IN3O6

Exact Mass:

Molecular Weight: 705.55

Elemental Analysis: C, 57.88; H, 4.57; I, 17.99; N, 5.96; O, 13.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
2648306-76-5 (cation)
Synonym
NIRHS; NIR HS; NIR-HS
IUPAC/Chemical Name
(E)-2-(2-(6-(2,4-Dinitrophenoxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide
InChi Key
OBQFEKRRPLICOT-IWSIBTJSSA-M
InChi Code
InChI=1S/C34H32N3O6.HI/c1-4-18-35-28-11-6-5-10-27(28)34(2,3)32(35)17-13-22-8-7-9-24-19-23-12-15-26(21-31(23)43-33(22)24)42-30-16-14-25(36(38)39)20-29(30)37(40)41;/h5-6,10-17,19-21H,4,7-9,18H2,1-3H3;1H/q+1;/p-1/b17-13+;
SMILES Code
CCC[N+]1=C(/C=C/C2=C3C(CCC2)=CC4=C(C=C(OC5=CC=C([N+]([O-])=O)C=C5[N+]([O-])=O)C=C4)O3)C(C)(C)C6=C1C=CC=C6.[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 705.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhou L, Lu D, Wang Q, Liu S, Lin Q, Sun H. Molecular engineering of a mitochondrial-targeting two-photon in and near-infrared out fluorescent probe for gaseous signal molecules H(2)S in deep tissue bioimaging. Biosens Bioelectron. 2017 May 15;91:699-705. doi: 10.1016/j.bios.2016.12.055. Epub 2016 Dec 28. PubMed PMID: 28126659. 2: Zhang L, Zheng XE, Zou F, Shang Y, Meng W, Lai E, Xu Z, Liu Y, Zhao J. A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice. Sci Rep. 2016 Jan 8;6:18868. doi: 10.1038/srep18868. PubMed PMID: 26743682; PubMed Central PMCID: PMC4705538.