MedKoo Cat#: 564815 | Name: TFIIH Modulator-19
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TFIIH Modulator-19 is a small molecule destabilization inducer of the trichothiodystrophy group A protein (TTD-A or p8) dimerization which modulates TFIIH transcriptional activity.

Chemical Structure

TFIIH Modulator-19
CAS#363-03-1

Theoretical Analysis

MedKoo Cat#: 564815

Name: TFIIH Modulator-19

CAS#: 363-03-1

Chemical Formula: C12H8O2

Exact Mass: 184.0524

Molecular Weight: 184.19

Elemental Analysis: C, 78.25; H, 4.38; O, 17.37

Price and Availability

Size Price Availability Quantity
5g USD 315.00
25g USD 850.00
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Related CAS #
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Synonym
TFIIH Modulator19; TFIIH Modulator 19; TFIIH Modulator-19
IUPAC/Chemical Name
2-Phenyl-1,4-benzoquinone
InChi Key
RLQZIECDMISZHS-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H
SMILES Code
O=C(C=C1)C=C(C2=CC=CC=C2)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 184.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pinho-Ribeiro FA, Hohmann MS, Borghi SM, Zarpelon AC, Guazelli CF, Manchope MF, Casagrande R, Verri WA Jr. Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: role of TRPV1, oxidative stress, cytokines and NF-κB. Chem Biol Interact. 2015 Feb 25;228:88-99. doi: 10.1016/j.cbi.2015.01.011. Epub 2015 Jan 21. PubMed PMID: 25617481.