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MedKoo Cat#: 564814 | Name: TFIIH Modulator-12
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TFIIH Modulator-12 is a small molecule destabilization inducer of the trichothiodystrophy group A protein (TTD-A or p8) dimerization which modulates TFIIH transcriptional activity.

Chemical Structure

TFIIH Modulator-12
CAS#1079-21-6

Theoretical Analysis

MedKoo Cat#: 564814

Name: TFIIH Modulator-12

CAS#: 1079-21-6

Chemical Formula: C12H10O2

Exact Mass: 186.0681

Molecular Weight: 186.21

Elemental Analysis: C, 77.40; H, 5.41; O, 17.18

Price and Availability

Size Price Availability Quantity
25g USD 215.00
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Related CAS #
No Data
Synonym
TFIIH Modulator12; TFIIH Modulator 12; TFIIH Modulator-12
IUPAC/Chemical Name
2,5-Biphenyldiol; [1,1'-biphenyl]-2,5-diol
InChi Key
XCZKKZXWDBOGPA-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H
SMILES Code
OC1=CC(C2=CC=CC=C2)=C(O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 186.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakata Y, Nishi K, Nishimoto S, Sugahara T. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway. J Toxicol Sci. 2013;38(3):325-35. PubMed PMID: 23665931.