Atorvastatin, (+/-)- | CAS# 110862-48-1 | Hydroxymethylglutaryl-CoA Reductase Inhibitor

MedKoo Cat#: 573312 | Name: Atorvastatin, (+/-)-

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Atorvastatin, (+/-)- is a Hydroxymethylglutaryl-CoA reductase inhibitor.

Chemical Structure

Atorvastatin, (+/-)-

CAS#110862-48-1

Theoretical Analysis

MedKoo Cat#: 573312

Name: Atorvastatin, (+/-)-

CAS#: 110862-48-1

Chemical Formula: C33H35FN2O5

Exact Mass: 558.2530

Molecular Weight: 558.65

Elemental Analysis: C, 70.95; H, 6.32; F, 3.40; N, 5.01; O, 14.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Atorvastatin, (+/-)-

IUPAC/Chemical Name

1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-, (betaR,deltaR)-rel-

InChi Key

XUKUURHRXDUEBC-SVBPBHIXSA-N

InChi Code

1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m0/s1

SMILES Code

c1(c(n(CC[C@@H](C[C@@H](CC(=O)O)O)O)c(c1C(Nc1ccccc1)=O)C(C)C)c1ccc(F)cc1)c1ccccc1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 558.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yang B, Sun J, Yuan Y, Sun Z. Effects of atorvastatin on autophagy in skeletal muscles of diabetic rats. J Diabetes Investig. 2018 Jul;9(4):753-761. doi: 10.1111/jdi.12789. Epub 2018 Jan 30. PubMed PMID: 29245171; PubMed Central PMCID: PMC6031525. 2: Qiu S, Zhuo W, Sun C, Su Z, Yan A, Shen L. Effects of atorvastatin on chronic subdural hematoma: A systematic review. Medicine (Baltimore). 2017 Jun;96(26):e7290. doi: 10.1097/MD.0000000000007290. Review. PubMed PMID: 28658127; PubMed Central PMCID: PMC5500049. 3: El-Nabarawi N, El-Wakd M, Salem M. Atorvastatin, a double weapon in osteoporosis treatment: an experimental and clinical study. Drug Des Devel Ther. 2017 May 2;11:1383-1391. doi: 10.2147/DDDT.S133020. eCollection 2017. PubMed PMID: 28496308; PubMed Central PMCID: PMC5422318.