ACAF4 | Neurotrophic Agent

MedKoo Cat#: 564778 | Name: ACAF4

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ACAF4 is a neurotrophic agent which significantly increases survival in PC12 neuronal cells and enhances the effect of nerve growth factor (NGF). ACAF4 induces neurite outgrowth, and modulates ERK1/2 and AKT signaling pathways.

Chemical Structure

ACAF4

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564778

Name: ACAF4

CAS#: NONE

Chemical Formula: C13H17NO3

Exact Mass: 235.1208

Molecular Weight: 235.28

Elemental Analysis: C, 66.36; H, 7.28; N, 5.95; O, 20.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ACAF-4; ACAF 4; ACAF4

IUPAC/Chemical Name

N-Butyl-3-(3,4-dihydroxy-phenyl)-acrylamide

InChi Key

HWCLPNBZZHKVDI-FNORWQNLSA-N

InChi Code

InChI=1S/C13H17NO3/c1-2-3-8-14-13(17)7-5-10-4-6-11(15)12(16)9-10/h4-7,9,15-16H,2-3,8H2,1H3,(H,14,17)/b7-5+

SMILES Code

O=C(NCCCC)/C=C/C1=CC=C(O)C(O)=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 235.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Moosavi F, Hosseini R, Rajaian H, Silva T, Magalhães E Silva D, Saso L, Edraki N, Miri R, Borges F, Firuzi O. Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents. Bioorg Med Chem. 2017 Jun 15;25(12):3235-3246. doi: 10.1016/j.bmc.2017.04.026. Epub 2017 Apr 27. PubMed PMID: 28495385.